Zygophyllum gaetulum pdf


















The two active compounds are triterpenene acid bisdesmo- present research was undertaken to evaluate a possible sides with different sugar residues at C-3 and C of antispasmodic activity induced by the extracts, partially the aglycones. In the course of our research program on African medic- inal plants, we investigated Zygophyllum gaetulum Emb.

In a South of Morocco. The plant was identified by Dr. Extraction and Isolation Address correspondence to: Dr. Aquino, Dipartimento di Air-dried and powdered aerial parts of Z. Montesano 49, , Napoli, Italy. Fractions of 8 ml were col- Capasso et al. This procedure gave pure DMSO up to ml was added to the organ bath to compounds 1 30 mg , 2 12 mg , and 3 9 mg from determine the baseline contraction.

The effects of the fraction B, 3 6 mg , 4 15 mg , 5 9 mg and 6 10 mg extracts, partially purified fractions and pure com- from fractions E and I, which were identified by their pounds on the electrically-induced contractions of NMR spectra as compared with literature data Safir et guinea-pig ileum E.

D-glucopyranosyl ester zygophyloside M previously reported in Z. Glycoside Morphine Withdrawal on Guinea-pig Ileum 4 was identified as 3b-O-b-D-glucopyranosyl-quinovic The experimental procedure was that described previ- acidO-b-D-glucopyranosyl ester previously iso- ously Capasso et al. Figure 2 shows a typical lated for the first time from Guettarda platypoda tracing of morphine withdrawal in vitro.

Aquino et al. The administration of the glucopyranosyl ester zygophyloside G and glycoside extracts, partially purified fractions and pure com- 6 as 3b-O-[b-D-2—O-sulphonylquinovopyranosyl]- pounds 1—6 was performed according to the following quinovic acidO-[b-D-glucopyranosyl ester zygo- schedule: phyloside E previously isolated from Z.

Figure 1 b electrical stimulation 10—20 min shows glycosides 1—6 from Zygophyllum gaetulum. Male Charles River guinea-pigs — g d washout and Ach response were used for all the experiments. Food and water were available ad stimulation injected 10 min before morphine fol- libitum.

Glycosides 1—6 from Zygophyllum gaetulum. Louis, U. Each experiment was performed on at least 6 to 9 isolated preparations from different animals. Parameter evaluation. Four parameters were evaluated as previously described by Capasso et al.

The IC50 values were pared. An IC50 was calculated according to the method mg C. Typical tracing of morphine withdrawal on guinea-pig ileum. Patients and Methods: We made this study on subjects men divided into four groups 30 healthy control Seaweeds are potential sources of bioactive molecules.

They are known to be rich sources of proteins, carbohydrates, lipids, vitamins, minerals, and other secondary metabolites. To evaluate the presence of these compounds in marine macroalgae collected from Veraval coast of Gujarat, present studies was carried out. The methanol extract of six macroalgae species Ulva lactuca, Ulva faciata, Acantho Topical formulations may contribute to the reduction of oxidative stress in the skin. Banana peel is a fruit waste with antioxidant activity that is not yet included in a topical formulation.

The aim of this study was to evaluate the antioxidant and anti-aging activity of a cream formulation containing a lyophilized extract of banana peel.

The banana peel was extracted with ethanol, and a cream fo A new series of Schiff's base compounds were synthesized by condensation of 1- 4-amino-4 phenyl 3-phenyl triazeneol and substituted aldehyde and gave high yields of target compounds.

Antimicrobial activity of compounds has been tested against bacterial and fungal species, namely gram-positive bacteria as S. The antibacterial property of three Himalayan Oaks species Quercus floribunda, Q.

It is an open access online and print International Journal published monthly. Website: www. A review of natural products and plants as potential antidiabetic drugs. Jour- nal of Ethnopharmacology 27, — The authors are grateful to International Foun- Jaouhari, J. Current status of oral agents in diabetes.

Ouhammou, Labo- Lazrek, H. B, Jaouhari, J. Larhsini for helpful Maroc. References Litchfield, J. A simplified method of evaluating dose — effect experiments.

Journal of Pharmaco- logical and Experimental Therapeutics 96, 99 — Aclinou, P. Plantes des Aures III. Maubert, P. Andersson, A. Effects of glipizide on the Melander, A.

Sulphonylureas in the treatment of non- insulin production by isolated mouse pancreatic islets. In: Nattrass, M, Hale, P. Acta Endocrinologica , 37 — 41 [suppl]. Non-in- Dodet, B. Biofutur sulin-dependent diabetes. A study of the hypoglucemic effect of some infarction and coronary heart disease mortality in a mid- Mexican plants. Journal of Ethnopharmacology 12, — dle-aged population.

Diabetologia 19, — In: Malaisse, W. Diabetes 39, A [suppl]. Excerpta Medica, Amsterdam, p. Twaij, H. Some Skim, F. Zygophyllum gaetulum: a study of its gation on Centaurea phyllocephala. Journal of Ethnophar- hypoglycemic activity in rats. Annales des Pharmaceu- macology 9, — Zimmet, P. Type II non insulin dependent diabetes: an Stenman, S. Diabetologia 22, — Related Papers The hypoglycemic activity of Zygophyllum gaetulum extracts in alloxan-induced hyperglycemic rats By Hassan Lazrek.

Hypoglycaemic effect of the lyophilised aqueous extract of Ajuga iva in normal and streptozotocin diabetic rats By jaouad hilaly. Hypoglycaemic effect of the lyophilised aqueous extract of Ajuga i6a in normal and streptozotocin diabetic rats By jaouad hilaly. Studies on the glycemic and lipidemic effect of Murraya koenigii in experimental animals By Santosh Kumar Singh. Download PDF.



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